Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 27;114(11):E2096–E2105. doi: 10.1073/pnas.1620813114

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. S6. — (A and B) Interatomic distance distributions of ASK1(88–658) (A) and ASK1(88–941) (B). (C) Overlay of experimental scattering data (black circles) and scattering profile calculated using BUNCH for the model of ASK1(88–941) W476S. A Guinier plot for the dataset is shown below, indicating that aggregates do not measurably contribute to the scattering profile. (D) Interatomic distance distributions of ASK1(88–941) W476S. (E) Surface representation of the BUNCH model of ASK1(88–941) W476S, with the thioredoxin-binding domain in gray, the TPR region in yellow, and the pleckstrin homology domain in purple. Residues that affect activity when mutated are indicated in red (F623 and D632) and blue (W476). Agreement between the experimental data and the calculated scatter pattern is indicated by χ = 0.55.