Animals were inoculated with virus on day 0, which corresponded to day 123 of immunization schedule for groups G1 to G4. G1 = 1× Δ5 virus (red), G2 = DD (green), G3 = DM (blue), G4 = control saline (orange), G5 = safety study (black). For each cytokine, the box plots show the first and third quartiles, together with the medians of the cytokine expressions.