Table 1.
Membrane and synaptic response properties for AIC neurons acutely isolated from control (ethanol naive) and ethanol-exposed animals divided into two rearing conditions
| Membrane Potential (mV) | Membrane Resistance (MΩ) | EPSC decay (msec) | Paired Pulse Ratio | sEPSC amp (pA) | sEPSC IEI (msec) | sEPSC decay (msec) | |
|---|---|---|---|---|---|---|---|
| Mother-Reared Control | −66.1 ± 0.8 (7 cells, 3 animals) | 295.7 ± 35.0 (12 cell 3 animals) | 21.5 ± 3.0 (7 cells, 3 animals) | 1.05 ± 0.07 (7 cells, 3 animals) | 5.1 ± 0.7 (7 cell. 3 animals) | 194.9 ± 27.6 (7 cells, 3 animals) | 3.1 ± 0.7 (7 cells. 3 animals) |
| Nursery-Reared Control | −70.0 ± 1.8 (8 cells, 3 animals)* | 228.7 ± 29.6 (9 cells, 3 animals) | 26.2 ± 4.8 (5 cells, 3 animals) | 0.95 ± 0.12 (5 cells, 3 animals) | 7.6 ± 1.0 (6 cells, 3 animals) | 145.6 ± 11.7 (6 cells, 3 animals)* | 7.6 ± 0.8 (6 cells, 3 animals) |
| Mother-Reared EtOH | −58.4 ± 2.4 (11 cells, 4 animals)# | 177.2 ± 23.3 (12 cells, 4 animals)# | 23.9 ± 3.6 (13 cells, 4 animals) | 0.85 ± 0.06 (11 cells, 4 animals)# | 7.4 ± 1.3 (5 cells, 3 animals) | 106.7 ± 25.2 (5 cells, 3 animals)# | 7.6 ± 1.3 (5 cells, 3 animals)# |
| Nursery-Reared EtOH | −60.8 ± 1.9 (8 cells, 4 animals)# | 235. ± 61.0 (7 cells, 3 animals) | 22.3 ± 2.8 (8 cells, 4 animals) | 0.93 ± 0.03 (5 cells, 4 animals) | 6.7 ± 1.9 (2 cells, 2 animals) | 111.1 ± 10.7 (2 cells, 2 animals) | 6.5 ± 2.6 (2 cells, 2 animals) |
Values represent mean ± SEM. Parenthetical numbers represent number of cells studied.
*
Between rearing conditions,
#
between ethanol treatment. p<0.05. unpaired t-test.