SB-T-121205 inhibits the EMT process in MCF-7/PTX cells. (A) Cell morphology observed by microscopy in MCF-7/PTX cells treated with paclitaxel alone or SB-T-121205 alone (original magnification, ×100). (B) The effect of paclitaxel or SB-T-121205 on mammosphere forming ability of MCF-7/PTX cells was examined (original magnification, ×100). (C) Expression of E-cadherin, N-cadherin and vimentin after treated with paclitaxel or SB-T-121205, was measured by western blot analysis. Data are shown as mean ± SD from three experiments and β-actin was used as loading control, *P<0.05, **P<0.01 vs. control group.