Figure 5.

SB-T-121205 inhibits the migration and invasion abilities of MDA-MB-453 cells. (A) Migration of MDA-MB-453 cells treated with paclitaxel alone (55 nM) or SB-T-121205 alone (19.5 and 39 nM) was determined by wound healing assay (original magnification, ×100). (B) Invasiveness of MDA-MB-453 cells treated with paclitaxel or SB-T-121205 was detected by Transwell invasion assay (original magnification, ×100). Data are shown as mean ± SD from three experiments, ^*P<0.05, ^**P<0.01 vs. control group.