Table I.
The effect of paclitaxel and new-generation taxanes on cell viability in MCF-7/PTX cells.a
| Taxane | IC50 (nM) | Taxane | IC50 (nM) |
|---|---|---|---|
| SB-T-1214 | 80.50±7.62 | SB-T-121303 | 21.67±2.25 |
| SB-T-101141 | 66.66±5.59 | SB-T-12301 | 54.59±4.61 |
| SB-T-121205 | 19.01±2.03 | SB-T-121405 | 34.90±2.97 |
| SB-T-121605 | 31.43±2.84 | SB-T-1230105 | 119.05±9.68 |
| Paclitaxel | 2290.87±125.18 |
a
Cell were treated with various concentrations of taxanes and IC50 values were calculated. Data were presented as mean ± SD from three independent experiments.