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. 2016 Dec 13;39(2):297–306. doi: 10.3892/ijmm.2016.2828

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Copyright: © Luo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Ulinastatin (UTI) post-treatment reduces the lung wet/dry weight ratio and myeloperoxidase (MPO) activity in rats with lipopolysaccharide (LPS)-induced acute lung injury (ALI). Rats were administered an intraperitoneal injection of UTI (5,000, 10,000 or 20,000 U/kg) 30 min after the LPS injection. (A) The lung wet/dry weight ratio and (B) the MPO activity were determined at 24 h after the LPS administration. The data are presented as the means ± SD (n=20 rats per group). ^*P<0.05 compared with the LPS group; #P<0.01 compared with the LPS group.