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. 2017 Mar 20;12(3):e0173899. doi: 10.1371/journal.pone.0173899

Table 2. Independent predictors of new-onset acute myocardial infarction.

Variables AMI STEMI NSTEMI
N (%) AHRa (95% CI) P-value N (%) AHRa (95% CI) P-value N (%) AHRa (95% CI) P-value
Age Group
    <40 y/o 35 (0.04%) 1.00 20 (0.02%) 1.00 15 (0.02%) 1.00
    40-50 y/o 136 (0.20%) 4.38 (3.02–6.35) <0.001* 56 (0.08%) 3.21 (1.92–5.35) <0.001* 80 (0.12%) 5.80 (3.34–10.09) <0.001*
    50-60 y/o 281 (0.38%) 7.80 (5.48–11.10) <0.001* 93 (0.13%) 4.88 (3.00–7.94) <0.001* 188 (0.26%) 12.10 (7.14–20.49) <0.001*
    ≧60 y/o 1155 (1.14%) 17.35 (12.34–24.40) <0.001* 289 (0.29%) 9.89 (6.22–15.74) <0.001* 866 (0.85%) 33.67 (20.12–56.35) <0.001*
Gender
    Female 570 (0.33%) 1.00 119 (0.07%) 1.00 451 (0.26%) 1.00
    Male 1037 (0.69%) 1.99 (1.80–2.21) <0.001* 339 (0.23%) 3.30 (2.68–4.07) <0.001* 698 (0.46%) 1.80 (1.60–2.03) <0.001*
GERD
    No 1236 (0.46%) 1.00 359 (0.13%) 1.00 877 (0.33%) 1.00
    Yes 371 (0.68%) 1.48 (1.31–1.66) <0.001* 99 (0.18%) 1.22 (0.97–1.53) 0.086 272 (0.50%) 1.33 (1.15–1.53) <0.001*
Hypertension
    No 938 (0.33%) 1.00 293 (0.10%) 1.00 645 (0.23%) 1.00
    Yes 669 (1.53%) 1.70 (1.52–1.89) <0.001* 165 (0.38%) 1.70 (1.38–2.11) <0.001* 504 (1.15%) 1.79 (1.57–2.03) <0.001*
Diabetes
    No 1258 (0.41%) 1.00 387 (0.13%) 1.00 871 (0.28%) 1.00
    Yes 349 (2.11%) 2.02 (1.78–2.30) <0.001* 71 (0.43%) 1.63 (1.24–2.15) <0.001* 278 (1.68%) 2.48 (2.14–2.87) <0.001*
Hyperlipidemia
    No 1357 (0.44%) 1.00 399 (0.13%) 1.00 958 (0.31%) 1.00
    Yes 250 (1.69%) 1.59 (1.38–1.83) <0.001* 59 (0.40%) 1.43 (1.07–1.91) 0.017* 191 (1.29%) 1.48 (1.25–1.75) <0.001*
Congestive Heart Failure
    No 1569 (0.49%) 1.00 451 (0.14%) 1.00 1118 (0.35%) 1.00
    Yes 38 (2.09%) 1.49 (1.08–2.06) 0.016* 7 (0.38%) 1.29 (0.61–2.73) 0.508 31 (1.70%) 1.90 (1.32–2.74) 0.001*
Ischemic Stroke
    No 1556 (0.49%) 1 445 (0.14%) 1 1111 (0.35%) 1
    Yes 51 (1.51%) 0.86 (0.65–1.14) 0.297 13 (0.39%) 1.04 (0.59–1.82) 0.899 38 (1.13%) 1.02 (0.73–1.41) 0.927

a Cox's proportional hazards model; AMI, acute myocardial infarction; STEMI, ST elevation acute myocardial infarction; NSTEMI, Non-ST elevation acute myocardial infarction; AHR, adjusted hazard ratio; CI, confidence interval.

*P-value < 0.05 was considered statistically significant after test.