Table 2.
Copy Number Variations Seen in Patient (No. 395)-Derived Xenograft
| Type | Gene Name | Alteration | Sig. Ratio | Copy Number | Sig. Exon |
|---|---|---|---|---|---|
| Known | CDKN2A | Deletion | −9.8149 | 0.00222 | 5 |
| Known | TP53 | Deletion | −1.0027 | 0.998127 | 13 |
| Known | VHL | Deletion | −1.07139 | 0.951723 | 3 |
| Unknown | DDR2 | Amplification | 0.900786 | 3.734165 | 15 |
| Unknown | SRC | Amplification | 0.931351 | 3.814123 | 11 |
| Unknown | TOP1 | Amplification | 0.987788 | 3.966284 | 21 |
| Unknown | AURKB | Deletion | −0.83248 | 1.12313 | 8 |
| Unknown | FLT3 | Deletion | −0.88982 | 1.079362 | 25 |
| Unknown | MTOR | Deletion | −0.80689 | 1.143227 | 45 |
| Unknown | PTCH2 | Deletion | −0.83586 | 1.120501 | 19 |