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Pharmacokinetic parameter results
| Samples | Cmax, ng/mL | Tmax, minutes | Relative bioavailability | Absolute bioavailability | AUC, ng·h/mL |
|---|---|---|---|---|---|
| Marketed preparation (iv) | 2,700±67 | 30 | – | – | 2,842.5 |
| Drug solution (oral) | 1,750±43 | 60 | – | 1.74 | 4,951.5 |
| Formulation suspension (oral) | 1,563±58 | 240 | 3.25 wrt oral drug solution | 5.66 | 16,089.75 |
Notes: Cmax, maximum plasma concentration; Tmax, time required to reach Cmax.
Abbreviations: AUC, area under the curve; iv, intravenous; wrt, with respect to.
