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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Horm Behav. 2017 Jan 4;89:98–103. doi: 10.1016/j.yhbeh.2016.12.013

Fig 1.

Fig 1

Tamoxifen (TAM), and ICI 182,780 (ICI) facilitated sexual receptivity, as measured by lordosis quotient (LQ), and reduced MPN MOP activation as measured by MOP immunoreactivity (MOPi) intensity levels. OVX rats were primed with 2 μg EB (sc) and treated 44 h later with either A) TAM or DMSO (ip) or B) lateral ventricle infusions of ICI or DMSO, 4 h later they were tested for sexual receptivity. Four days after the EB priming for behavior, rats were given the same EB priming followed by the same drug treatments and were perfused followed by MOP immunohistochemistry. The TAM and ICI treatments both facilitated lordosis and reduced MOPi staining intensity levels compared to the DMSO treated rats. ✱ = Significantly greater than DMSO (P < 0.001). † = Significantly less than DMSO (P < 0.001).