Table 1.

Groups and sample sizes investigated in this study.

Group	Genotype	Estradiol	Loading Condition	Sample Size (n)
1	WT	Placebo	NL	6 (Histology); 6 (PCR and μCT)
2	WT	Estradiol	NL	6 (Histology); 6 (PCR and μCT)
3	WT	Placebo	DOL	6 (Histology); 6 (PCR and μCT)
4	WT	Estradiol	DOL	6 (Histology); 6 (PCR and μCT)
5	ERβKO	Placebo	NL	6 (Histology); 6 (PCR and μCT)
6	ERβKO	Estradiol	NL	6 (Histology); 6 (PCR and μCT)
7	ERβKO	Placebo	DOL	6 (Histology); 6 (PCR and μCT)
8	ERβKO	Estradiol	DOL	6 (Histology); 6 (PCR and μCT)