Table 2.
Comparison of Patients with a widened A-V O2 difference with normal and elevated plasma lactate levels
| Variable | Total (N=96) | Lactate ≥2.1 (N=24) | Lactate < 2.1 (N=72) | P-value |
|---|---|---|---|---|
| Age, years | 57.01 ± 11.04 | 53.98 ± 12.93 | 58.02 ± 10.24 | 0.12 |
| Caucasian, No. (%) | 70 (73%) | 15 (63%) | 55 (76%) | 0.20 |
| Male, No. (%) | 74 (77%) | 20 (83%) | 54 (75%) | 0.58 |
| Bmi, Kg/m2 | 29.77 ± 5.93 | 29.70 ± 5.36 | 29.79 ± 6.15 | 0.95 |
| Bsa, m2 | 2.07 ± 0.27 | 2.09 ± 0.27 | 2.06 ± 0.27 | 0.75 |
| Intermacs profile, No. (%) | 0.019 | |||
| . Intermacs 1 | 45 (47%) | 17 (71%) | 28 (39%) | |
| . Intermacs 2 | 45 (47%) | 7 (29%) | 38 (53%) | |
| . Intermacs 3+ | 6 (6%) | 0 (0%) | 6 (8%) | |
| AVO2 | 7.63 ± 1.91 | 8.23 ± 1.97 | 7.43 ± 1.86 | 0.08 |
| Lactate, Median (Q1, Q3) | 1.5 (1.1, 2.1) | 2.6 (2.3, 4.7) | 1.3 (1.1, 1.6) | <.001 |
| RA pressure, mmHg | 16.95 ± 8.68 | 17.79 ± 7.17 | 16.66 ± 9.16 | 0.58 |
| Wedge pressure, mmHg | 28.28 ± 8.15 | 27.52 ± 7.86 | 28.53 ± 8.28 | 0.61 |
| Cardiac index, L/min m2 | 1.73 ± 0.44 | 1.58 ± 0.40 | 1.79 ± 0.45 | 0.049 |
| Cardiac output, L/min | 3.62 ± 1.10 | 3.37 ± 1.04 | 3.70 ± 1.11 | 0.21 |
| LV EF, % | 17.53 ± 6.83 | 16.48 ± 4.97 | 17.83 ± 7.28 | 0.43 |
| LVEDD, cm | 6.82 ± 1.16 | 6.75 ± 1.24 | 6.84 ± 1.14 | 0.75 |
| RV TEI | 0.65 ± 0.32 | 0.58 ± 0.22 | 0.67 ± 0.34 | 0.17 |
| Continuous Inotropes | 92.7% | 91% | 92.5% | 0.74 |
| Vasopressors | 13.5% | 20% | 14.3% | 0.48 |
| INR | 1.51 ± 0.44 | 1.71 ± 0.40 | 1.45 ± 0.43 | 0.012 |
| Hemoglobin, mg/dl | 10.79 ± 2.07 | 11.21 ± 2.58 | 10.61 ± 1.82 | 0.23 |
| AST, U/L, Median (Q1, Q3) | 47.0 (30.0, 142.0) | 126.0 (41.5, 216.0) | 42.0 (30.0, 83.0) | 0.013 |
| Glucose, mg/dl | 173 ±74 | 175 ±60 | 173 ± 52 | 0.87 |
| Albumin, g/dl | 3.42 ± 0.47 | 3.23 ± 0.35 | 3.48 ± 0.49 | 0.026 |
| Creatinine, g/dl | 1.68 ± 0.75 | 1.72 ± 0.60 | 1.66 ± 0.79 | 0.71 |