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. 2017 Mar 14;10:1603–1611. doi: 10.2147/OTT.S118151

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© 2017 Dai et al. This work is published and licensed by Dove Medical Press Limited

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TCF21 regulates key molecules of PI3K signaling and MMPs.

Notes: (A) Western blot analysis for TCF21, Kiss-1, PI3K, AKT, p-AKT, MMP2 and MMP9 in HT29 and HCT116 cells after transfection with TCF21, and the results of quantification in (B) HCT116 and (C) HT29 cells. The cells without any treatment were used as mock control, and the cells treated with empty lentivirus were used as negative control. Data are presented as mean ± SD. **P<0.01, ***P<0.001. HCT116 and HT29, human colorectal cancer cell lines.

Abbreviations: Lv, lentivirus; NC, negative control.