Table 2.

Multivariate Cox model analysis

Variables	RR	95% CI	P-value
Depth of invasion (T1 + T2 vs T3 + T4)	1.529	0.634–3.637	0.039
TNM stage (I+II vs III+IV)	2.330	1.189–4.565	0.014
Lymph node metastasis (yes vs no)	5.247	2.791–9.866	<0.001
TCF21 protein expression (low vs high)	0.271	0.142–0.517	<0.001

Abbreviations: CI, confidence interval; RR, relative risk; TNM, tumor-node-metastasis.