Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Identification and mapping of HU-resistant early replication origins. Early origins were identified by releasing cells synchronized at G2 into medium containing HU and BrdU. Only those sequences immediately adjacent to replication origins are expected to incorporate BrdU. The blue histogram represents BrdU enrichment along the chromosome. The replication timing profile is overlaid in red. Early BrdU-enriched peaks above the dashed black line (p < 0.001) are significantly enriched.
