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(A) Extensive cross regulation has been reported between the biosynthetic pathways of jadomycins (i.e., JdDS) and chloramphenicol (Cam) within S. venezuelae ISP5230. (B) The jadomycin biosynthetic gene cluster. Regulatory genes are colored in green, predicted promoter regions in red, angucycline biosynthetic structural genes in gray, sugar biosynthetic structural genes in blue, and jadL, which codes a predicted transport protein, is hatched.
