Table 1.
Baseline characteristics of all patients according to quartiles of tHcy levels.
| Q1 (<9.94), n = 150 | Q2 (9.94–12.7), n = 149 | Q3 (12.7–16.8), n = 147 | Q4 (>16.8), n = 148 | P | |
|---|---|---|---|---|---|
| Age, year∗ | 78 | 78 | 79 | 79 | 0.768 |
| Male, n (%) | 68 (45.3) | 68 (45.3) | 91 (61.9) | 96 (64.9) | 0.000 |
| Hypertension, n (%) | 111 (74.0) | 106 (71.1) | 102 (69.4) | 118 (79.7) | 0.197 |
| DM, n (%) | 49 (32.7) | 53 (35.6) | 36 (24.5) | 34 (23.0) | 0.043 |
| AF, n (%) | 30 (20.0) | 22 (14.8) | 23 (15.6) | 16 (10.8) | 0.179 |
| Dyslipidemia, n (%) | 42 (28.0) | 28 (18.8) | 25 (17.0) | 30 (20.3) | 0.097 |
| CAS, n (%) | 32 (21.3) | 23 (15.4) | 35 (26.9) | 40 (27.0) | 0.100 |
| Smoking, n (%) | 27 (18.0) | 28 (18.8) | 28 (19.0) | 40 (27.0) | 0.183 |
| Alcohol drinker, n (%) | 7 (4.7) | 7 (4.7) | 10 (6.8) | 12 (8.1) | 0.526 |
| Obesity, n (%) | 27 (18.0) | 28 (18.8) | 21 (14.3) | 25 (16.9) | 0.750 |
| TOAST subtype | 0.859 | ||||
| LA | 73 (48.7) | 82 (55.0) | 77 (52.4) | 85 (57.4) | |
| CE | 10 (6.7) | 15 (10.1) | 15 (10.2) | 14 (9.5) | |
| SA | 47 (31.3) | 32 (21.5) | 36 (24.5) | 32 (21.6) | |
| OE | 10 (6.7) | 9 (6.0) | 9 (6.1) | 7 (4.7) | |
| UE | 10 (6.7) | 11 (7.4) | 10 (6.8) | 10 (6.9) | |
| CHO, mmol/L∗ | 4.79 (1.29) | 4.84 (1.53) | 4.37 (1.32) | 4.71 (1.21) | 0.147 |
| TG, mmol/L∗ | 1.06 (0.62) | 1.05 (0.75) | 1.03 (0.77) | 1.07 (0.75) | 0.983 |
| HDL-C, mmol/L∗ | 1.01 (0.35) | 1.04 (0.42) | 1.02 (0.31) | 0.98 (0.32) | 0.599 |
| LDL-C, mmol/L∗ | 3.17 (1.20) | 2.95 (1.12) | 2.73 (1.05) | 3.03 (1.08) | 0.268 |
| FG, mmol/L∗ | 5.83 (2.93) | 5.61 (2.30) | 5.50 (2.18) | 5.57 (1.53) | 0.166 |
| hsCRP, mg/L∗ | 4.34 (15.72) | 4.26 (8.31) | 3.97 (12.25) | 5.29 (15.36) | 0.357 |
| Hcy, μmol/L | 8.75 (1.58) | 11.30 (1.25) | 14.50 (2.00) | 22.40 (14.35) | <0.001 |
| NIHSS∗ | 6.50 (10.75) | 6.00 (9.00) | 7.00 (11.00) | 8.00 (9.00) | 0.693 |
| Time # | 83.04 ± 50.94 | 80.38 ± 53.59 | 80.97 ± 49.87 | 84.65 ± 52.70 | 0.888 |
DM, diabetes mellitus; AF, atrial fibrillation; CAS, cerebral artery stenosis; CHO, cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FG, fasting glucose; hsCRP, high sensitivity C-reactive protein; Hcy, homocysteine. NIHSS, National Institutes of Health Stroke Scale.
Time represents hours from stroke onset.
∗Median (interquartile range); #Mean ± standard deviation.