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. 2017 Mar 21;8:322. doi: 10.3389/fimmu.2017.00322

Figure 3.

Figure 3

Pre-lung transplantation (LTx) IgG antibodies to apoptotic cells do not correlate with clinical outcome after LTx. Pre-LTx purified IgG levels against apoptotic endothelial cells (A,C) and Jurkat cells (B,D) were stratified according to either bronchiolitis obliterans syndrome (BOS) diagnosis (A,B) or the incidence of acute rejection (AR) (C,D). Neither BOS+ nor AR+ patients presented with different purified pre-LTx IgG levels. Therefore, no correlation between IgG reactivity against apoptotic cells and clinical outcome after LTx was observed. The data are represented as box and whiskers plot where the horizontal bar depicts the median value, the box both 25th and 75th percentiles, and the whiskers the minimum and maximum of the observed values. (B) Data normally distributed, unpaired t-test. (A,C,D) Data not-normally distributed, Mann–Whitney test. BOS+ n = 29, BOS− n = 51, AR+ n = 17, AR− n = 63.