Skip to main content
. 2017 Mar 21;10:79. doi: 10.3389/fnmol.2017.00079

Figure 2.

Figure 2

c-Fos and phospho (p)-extracellular signal-regulated kinase (ERK) expression in NP and Sham rats. (A) Histological clarification of rostral insular cortex (IC) with rat atlas. Subdivisions of the IC were included in the black square box. c-Fos- and p-ERK-positive cells in the AIV and AID were analyzed. AIV, agranular insular cortex ventral; AID, agranular insular cortex dorsal; DI, dysgranular insular cortex; GI, granular insular cortex; S2, secondary somatosensory cortex; Den, dorsal endopiriform nucleus; VCI, ventral part of claustrum; DCI, dorsal part of claustrum. (B) Microphotographs of c-FOS and p-ERK in the rostral IC (AIV and AID areas). The arrows mean positive cells for c-FOS or p-ERK. (C) Quantification of c-Fos- and (D) p-ERK-positive cells on POD3. (E) Quantification of c-Fos- and (F) p-ERK-positive cells on POD7. Scale bars, 200 μm. Data are presented as means ± SEM. *P < 0.05, **P < 0.01 vs. Sham.