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. 2017 Mar 21;10:79. doi: 10.3389/fnmol.2017.00079

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Copyright © 2017 Kwon, Han, Kim, Cha, Um, Bai, Hong and Lee.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in optical signals before and after treatment with rapamycin and vehicle. (A) Optical signals before and after vehicle treatment. (B) Optical signals before and after rapamycin treatment. (C) Peak amplitudes before and after vehicle and rapamycin treatments following peripheral electrical stimulation with 5.0 mA intensity. (D) Activated areas before and after vehicle and rapamycin treatments following peripheral electrical stimulation with 5.0 mA intensity. The peak amplitudes and activated areas induced by peripheral electrical stimulation after rapamycin treatment were reduced compared with those before rapamycin treatment. However, they are not significantly different in both before and after vehicle treatment. *P < 0.05, **P < 0.01.