Table 3. Changes in urine calcium excretion in 10 cases of Dent disease before and after treatment with dihydrochlorothiazide and potassium citrate.
Patient | UC/Ucr (g/gcr) |
Urine calcium excretion (mmol/kg/24 h) |
||||
---|---|---|---|---|---|---|
Before | After | Decreased percent | Before | After | Decreased percent | |
No.1 | 0.31 ± 0.07 | 0.15 ± 0.02 | 51.61% | 0.19 ± 0.02 | 0.09 ± 0.01 | 52.63% |
No.2 | 0.56 ± 0.12 | 0.25 ± 0.08 | 55.36% | 0.28 ± 0.03 | 0.13 ± 0.02 | 53.57% |
No.3 | 0.48 ± 0.13 | 0.23 ± 0.06 | 50.08% | 0.27 ± 0.01 | 0.13 ± 0.01 | 51.85% |
No.4 | 0.35 ± 0.09 | 0.17 ± 0.03 | 51.43% | 0.19 ± 0.01 | 0.08 ± 0.01 | 57.89% |
No.5 | 0.38 ± 0.10 | 0.17 ± 0.03 | 55.26% | 0.24 ± 0.02 | 0.10 ± 0.01 | 58.33% |
No.6* | 0.33 ± 0.09 | 0.16 ± 0.04 | 51.52% | 0.23 ± 0.02 | 0.10 ± 0.01 | 56.52% |
No.7* | 0.32 ± 0.10 | 0.15 ± 0.03 | 53.13% | 0.18 ± 0.01 | 0.09 ± 0.01 | 50.00% |
No.8 | 0.31 ± 0.09 | 0.15 ± 0.04 | 51.61% | 0.19 ± 0.02 | 0.08 ± 0.01 | 57.89% |
No.9 | 0.35 ± 0.09 | 0.16 ± 0.05 | 54.29% | 0.16 ± 0.02 | 0.07 ± 0.02 | 56.25% |
No.10 | 0.35 ± 0.12 | 0.16 ± 0.08 | 54.29% | 0.18 ± 0.03 | 0.08 ± 0.02 | 55.56% |
Statistics | t = 13.254 | p < 0.001 | t = 16.515 | p < 0.001 |
No.6 and No.7 are brothers; UC: Urine calcium; UCE: Urine calcium excretion; Ucr: Urine creatinine.