Table 4. Changes in urine protein excretion before and after treatment with Lotensin in 7 cases of Dent disease.
Patient | α1MG (mg/L) |
MA (mg/L) |
UPE (mg/kg/24 h) |
LMWP (%) |
||||
---|---|---|---|---|---|---|---|---|
Before | After | Before | After | Before | After | Before | After | |
No.1 | 402 ± 113 | 389 ± 135 | 285 ± 89 | 276 ± 84 | 64 ± 18 | 58 ± 17 | 61.3 ± 9.3 | 58.7 ± 6.8 |
No.2 | 349 ± 125 | 354 ± 133 | 301 ± 81 | 315 ± 89 | 58 ± 17 | 55 ± 18 | 53.1 ± 7.5 | 57.4 ± 8.3 |
No.3 | 305 ± 108 | 312 ± 112 | 257 ± 76 | 248 ± 78 | 55 ± 15 | 58 ± 13 | 53.5 ± 8.4 | 51.7 ± 9.6 |
No.5 | 375 ± 134 | 368 ± 129 | 268 ± 79 | 271 ± 75 | 53 ± 14 | 50 ± 16 | 56.5 ± 7.2 | 55.6 ± 9.2 |
No.6 | 382 ± 120 | 371 ± 127 | 256 ± 82 | 267 ± 85 | 53 ± 13 | 55 ± 15 | 59.5 ± 7.6 | 58.7 ± 8.2 |
No.9 | 341 ± 116 | 338 ± 107 | 239 ± 62 | 227 ± 58 | 56 ± 11 | 54 ± 12 | 56.1 ± 7.5 | 54.2 ± 6.7 |
No.10 | 355 ± 124 | 351 ± 115 | 248 ± 61 | 219 ± 63 | 57 ± 10 | 55 ± 14 | 55.9 ± 6.3 | 51.6 ± 6.8 |
Statistics | t = 1.303 | p = 0.240 | t = 0.785 | p = 0.462 | t = 1.341 | p = 0.229 | t = 1.131 | p = 0.301 |
α1MG: α1-microglobinuria; LMWP: Low molecular weight proteinuria; MA: Microalbuminuria; UPE: Urinary protein excretion.