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. 2016 Dec 22;66(4):427–440. doi: 10.1007/s00262-016-1945-z

Fig. 4.

Fig. 4

Levels of urinary neopterin, sTNF-R75 and sIL-2Rα (pro creatinine) at baseline, during and after BCG therapy. Patients were stratified by treatment outcome (BCG response vs. failure). Data represent mean ± 95% confidence interval (CI); *p < 0.05; **p < 0.01; ***p < 0.001; overall p value from a mixed model analysis for repeated measures between responders and non-responders; Mann–Whitney U tests for single time point comparisons. s soluble, TNF tumor necrosis factor, IL interleukin