Fig. 7.

Percentage ATP-values after different short- and long-time 2DG-treatments are shown. The data are taken from two representative experiments and show that the ATP-concentrations are persistently depressed throughout the entire times of the experiments. The electron micrograph shows parts of the cytoplasm of a HepG2 cell treated with 2DG for 5 h. Regular Golgi apparatus stacks are lacking; instead, Golgi bodies with densely packed membrane compartments dominate closely adjacent to cisternae of the RER filled with electron dense contents