Table 1.
Overview of cell lines and 2DG-concentrations used in various scientific studies
| Cell line | Source | Concentration of 2DG (mM) | References |
|---|---|---|---|
| 1420 | Pancreatic cancer (Homo sapiens) |
4 | Xi et al. (2011) |
| A549 | Lung carcinoma (Homo sapiens) |
5 and 100 | Djuzenova et al. (2009) |
| 100 | Wu et al. (2007) | ||
| BAEC | Aortic endothelial cells (Bovine) | 5 | Wang et al. (2011) |
| BT-549 | Breast cancer (Homo sapiens) |
4-12 | Aft et al. (2002) |
| C2C12 | Myoblast (Mus musculus) |
25 | Hong and Hagen (2015) |
| DU145 | Prostate cancer (Homo sapiens) |
20 | Li et al. (2015) |
| GaMG | Glioblastoma (Homo sapiens) |
5 and 100 | Djuzenova et al. (2009) |
| GIST-T1 GIST48 GIST48B GIST430 GIST882 |
Metastatic gastrointestinal stromal tumor (Homo sapiens) |
0.01–10 | Mühlenberg et al. (2015) |
| GL15 | Glioblastoma (Homo sapiens) |
5 | Zhang et al. (2006) |
| H460 | Large cell lung cancer (Homo sapiens) |
100 | Wu et al. (2007) |
| H1299 | Nonsmall cell lung carcinoma, derived from metastatic site: lymph node (Homo sapiens) |
1–100 | Kobayashi et al. (2015) |
| HCT116 | Colorectal cancer (Homo sapiens) |
0.5–20 | Ahadova et al. (2015) |
| 1–100 | Kobayashi et al. (2015) | ||
| HEK293T | Embryonic kidney (Homo sapiens) |
25 | Hong and Hagen (2015) |
| HeLa | Cervix cancer (Homo sapiens) |
1–10 | Kobayashi et al. (2015) |
| 4–10 | Lin et al. (2003) | ||
| 45 | Maehama et al. (1998) | ||
| Hep-2 (CCL-23) |
Epithelial cells from HeLa contaminant tissue (Homo sapiens) |
10 | Kavaliauskiene et al. (2015) |
| HepG2 | Epithelial hepatoblastoma (Homo sapiens) |
5 | Zhang et al. (2006) |
| 25 | Hong and Hagen (2015) | ||
| 50 | Ranftler et al. (2015) | ||
| HMEC | Mammary epithelial cells (Homo sapiens) |
20 | Li et al. (2015) |
| HT29-D4 | Colon carcinoma (Homo sapiens) |
5 | Zhang et al. (2006) |
| HT29 (HTB-38) |
Colon adenocarcinoma (Homo sapiens) |
10 | Kavaliauskiene et al. (2015) |
| HT1080 | Fibrosarcoma (Homo sapiens) |
5 and 100 | Djuzenova et al. (2009) |
| IGROV1 | Ovarian carcinoma (Homo sapiens) |
5 | Zhang et al. (2006) |
| LN-229 | Glioblastoma (Homo sapiens) |
1.6–50 | Wu et al. (2009) |
| MCF-7 | Breast cancer (Homo sapiens) |
0.5 | Oladghaffari et al. (2015) |
| 4–12 | Aft et al. (2002) | ||
| MDA-MB-231 | Breast cancer (Homo sapiens) |
20 | Li et al. (2015) |
| MDA-MB-435 | Melanoma (Homo sapiens) |
10 | Xi et al. (2011) |
| MDA-MB-468 | Breast cancer (Homo sapiens) |
4–12 | Aft et al. (2002) |
| MDCK | Madin-Darby canine kidney epithelial (Dog) |
25 | Hong and Hagen (2015) |
| MSTO-211H | Lung mesothelioma (Homo sapiens) |
5 | Zhang et al. (2006) |
| NCI-H28 | Lung mesothelioma (Homo sapiens) |
5 | Zhang et al. (2006) |
| NRK | Normal kidney (Rat) |
50 | del Valle et al. (1999) |
| PC3 | Prostate cancer (Homo sapiens) |
0.005 | Jangamreddy et al. (2015) |
| 0–20 | Jeon et al. (2015) | ||
| 20 | Li et al. (2015) | ||
| RPMI-2650 | Squamous cell carcinoma of the nasal septum (Homo sapiens) |
4 | Keenan et al. (2004) |
| SCC61 | Head and neck squamous cell carcinoma (Homo sapiens) |
5 | Zhang et al. (2006) |
| SH-EP | Neuroblastoma (Homo sapiens) |
15 | Hagenbuchner et al. (2015) |
| SKBR3 | Breast cancer (Homo sapiens) |
0.5 | Oladghaffari et al. (2015) |
| 4–12 | Aft et al. (2002) | ||
| 10 | Xi et al. (2011) | ||
| SKOV3 | Ovarian carcinoma (Homo sapiens) |
5 | Zhang et al. (2006) |
| SQ2OB | Head and neck squamous cell carcinoma (Homo sapiens) |
5 | Zhang et al. (2006) |
| SVEC4-10 | Lymphoid endothelial (Mus musculus) |
0–20 | Huang et al. (2015) |
| STA-NB1 STA-NB4 STA-NB8 STA-NB15 |
Neuroblastoma (Homo sapiens) |
15 | Hagenbuchner et al. (2015) |
| SW480 (CCL-228) |
colorectal adenocarcinoma (HOMO sapiens) |
10 | Kavaliauskiene et al. (2015) |
| SW620 | Colorectal cancer (Homo sapiens) |
1–20 | Muley et al. (2015) |
| T47D | Breast cancer (Homo sapiens) |
20 | Mustafa et al. (2015) |
| T98G | Glioblastoma (Homo sapiens) |
1.6–50 | Wu et al. (2009) |
| U87-MG | Glioblastoma-astrocytoma (Homo sapiens) |
5 and 100 | Djuzenova et al. (2009) |
| U251 | Glioblastoma (Homo sapiens) |
5 | Zhang et al. (2006) |