Summary of experimental approach. (A) Clip compression injury model at the C7-T1 level. From left to right representative images of: 1) a modified aneurism clip used to impact the spinal cord; 2) clip compression injury of the spinal cord; 3) a spinal cord after laminectomy (Sham) and after clip compression (SCI). Note the bruising of the spinal cord created immediately after clip injury. (B) Table summarizing the time-points post-SCI studied and the experimental approaches taken for the characterization of the antibody responses after cervical SCI. SCI, spinal cord injury; WB, Western blot; IF, immunofluorescence; CSF, cerebrospinal fluid; ELISA, enzyme-linked immunosorbent assay; IHC, immunohistochemistry. Pictures of panel (A) are courtesy of Dr. Rakhi Sharma and Jared Wilcox. Color image is available online at www.liebertpub.com/neu