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. 2017 Mar 21;7:44826. doi: 10.1038/srep44826

Figure 3. Effects of acetylation at K322 and K392 on ICL1 enzyme activities.

Figure 3

(A) Isocitrate lyase (ICL) and methylcitrate lyase (B) activities of purified ICL1 mutant proteins. The data were normalized against the activity of WT protein and plotted as mean ± s.d. (n = 3). Statistical analysis was performed by one-way ANOVA comparing each mutant protein with WT. *p < 0.05; **p < 0.01; ***p < 0.001. (C) Isocitrate lyase (ICL) and methylcitrate lyase (MCL) activities of purified ICL1 proteins in which K322 or K392 was acetylated. The data were normalized against the activity of WT protein and plotted as mean ± s.d. (n = 3). Statistical analysis was performed by Student’s t-test comparing each mutant protein with WT. **p < 0.01; ***p < 0.001.