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. 2017 Mar 20;16:123. doi: 10.1186/s12936-017-1768-1

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — HRP2 RDT sensitivity, slide positivity rate and rainfall by study site and month. Rainfall is plotted in millimeters per month on the left y axis. Sensitivity and slide positivity rate are plotted on the right y axis. The navy band represents the 95% confidence interval for sensitivity. The dashed line represents the slide positivity rate. There was significant variation in HRP2 RDT sensitivity across the study sites and a decline in RDT sensitivity was noted following a decline in malaria transmission. In Rukara, monthly estimates of HRP2 RDT sensitivity ranged from 90 to 97%. Conversely, in Kibirizi, a site subject to two rounds of IRS during the study period, the sensitivity of the HRP2 RDT declined from 88 to 67% as the slide positivity rate fell from 46 to 3%. SPR slide positivity rate; CI confidence interval