Fig. 6.

Chrysin inhibited HCC-LM3 xenograft growth in vivo. Nude mice with HCC-LM3 xenograft were randomly divided to groups when tumor volume reached 50 to 100 mm³. 30 mg/kg chrysin was administrated three times weekly by intraperitoneal injection. a, photograph of tumors in vehicle and chrysin-treated group; b, the change of body weight of tumor bearing mice; c, tumor growth curve in vehicle and treated group; d, tumor weight in vehicle and chrysin group; e, tumor tissues were subjected to immunohistochemistry staining with indicated antibodies to detect the change of HK-2, Ki67 after chrysin treatment