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. 2017 Mar 20;5:25. doi: 10.1186/s40560-017-0219-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Serum CT-proET-1 concentrations in critically ill patients and sepsis. a Serum levels of CT-proET-1, at the time of admission to the ICU, were significantly higher in critically ill patients than in healthy controls (p < 0.001; U test). b CT-proET-1 levels were significantly higher in patients with sepsis (p < 0.001) compared to ICU patients without sepsis. c When matched 1:1 with non-sepsis patients for APACHE-II score, age, and sex, CT-proET-1 levels were significantly higher in patients with sepsis compared to ICU patients without sepsis (p < 0.001)