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. 2017 Mar 20;19:60. doi: 10.1186/s13075-017-1271-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Soluble endothelial biomarker concentrations in patients with systemic sclerosis (SSc) compared with healthy control subjects (HC). a Vascular endothelial growth factor (VEGF). b Endothelin-1. c Soluble fractalkine (s-Fractalkine). d Correlation between s-Fractalkine and CD34⁺CD45⁻ endothelial progenitor cell (EPC) counts (nb). Correlation was established using the non-parametric Spearman’s correlation coefficient (r _s). * P < 0.05; *** P < 0.0005. n.s = non-significant