Table 1.
Demographic characteristics and cardiovascular risk factors of the subjects
| Patients with SSc (n = 45) | Control subjects (n = 41) | P value | |
|---|---|---|---|
| Sex, male/female, n | 1/44 | 3/38 | 0.3437 |
| Age, years, median [IQR] | 61.49 (±11.95) 60.4 [51.5–72.4] | 56.09 (±7.82) 56 [53.6–59.6] | 0.0375 |
| BMI, kg/m2, median [IQR] | 23.05 (±4.63) 22.5 [20.2–23.8] | 25.3 (±3.75) 24.9 [22.8–28.3] | 0.0022 |
| Systolic blood pressure, mmHg | 119.11 (±16.95) 120 [105–130.25] | 127.7 (±14.1) 126 [119.25–135.25] | 0.0141 |
| Diastolic blood pressure, mmHg | 71.86 (±8.91) 72.5 [67.75–78.25] | 79.15 (±9.71) 79 [73–84.25] | 0.0006 |
| Resting heart rate, beats/minute | 71.25 (±10.24) 70.5 [64–76.25] | 68.95 (±9.93) 70 [62.75–74] | 0.3001 |
| LDL cholesterol, g/L | 3.29 (±1.32) 3.2 [2.36–4.28] | 3.69 (±0.79) 3.59 [3.17–4.13] | 0.0978 |
| HDL cholesterol, g/L | 1.72 (±0.43) 1.71 [1.4–1.95] | 1.59 (±0.43) 1.51 [1.34–1.85] | 0.1848 |
| Triglycerides, g/L | 1.14 (±0.47) 0.93 [0.81–1.48] | 1.4 (±0.74) 1.25 [0.88–1.66] | 0.1303 |
| Carotid-radial pulse wave velocity, m/second | 11.05 (±3.32) 10.5 [8.16–13] | 10.11 (±3.01) 9.46 [7.62–12.05] | 0.1855 |
| Flow-mediated dilation, % | 9.87 (±6.97) 9.3 [5.8–14.76] | 15.29 (±8.75) 12.35 [9.09–21.38] | 0.0084 |
Abbreviations: BMI Body mass index, HDL High-density lipoprotein, LDL Low-density lipoprotein, SSc Systemic sclerosis
Variables are described using mean (±SD) and median [IQR]