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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Phys Chem Chem Phys. 2017 Feb 15;19(7):5028–5036. doi: 10.1039/c6cp08924k

Scheme 2.

Scheme 2

An example showing how the free energy (G) of any conformation state in the system can be calculated if all of the microscopic rate constants are known. For convenience, the free energy of the fully disordered state, G0, is set to zero.