Table 2.
Linear regression analysis of the association between plasma TGF-β (per doubling) and eGFR and ACR
| Model | eGFR | Urinary ACR | ||
|---|---|---|---|---|
| β (95% C.I.) | p-value | β (95% C.I.) | p-value | |
| M0 | –1.54 (–2.44,–0.63) |
<0.001 | 0.09 (0,0.18) |
0.055 |
| M1 | –1.41 (–2.27,–0.55) |
<0.001 | 0.06 (–0.03,0.15) |
0.19 |
| M2 | –1.18 (–2.03,–0.32) |
0.007 | 0.04 (–0.05,013) |
0.35 |
M0: unadjusted analysis
M1: M0 + age, male gender, and black race
M2: M1 + current smoking status, hypertension, diabetes mellitus, body mass index, LDL-cholesterol, triglycerides, history of cardiovascular disease, and C-reactive protein