Table 3.
Study | n | n COPD patients | n controls | Age (mean ± SD) | FEV1 (L) (mean ± SD) | FEV1/FVC% (mean ± SD) | Pack-years (mean ± SD) | %Current smoker | % Female |
---|---|---|---|---|---|---|---|---|---|
Qiu et al.[23] | 1085 | 620 | 325 | 57.3 ± 8.1 | N/A | 54.4 ± 19.8 | 41.7 ± 26.2 | 36.5 | 45.6 |
369 | 181 | 109 | 47.5 ± 7.1 | N/A | 54.3 ± 21.1 | 28.7 ± 23.6 | 27.9 | 64 | |
Bell et al. [22] | 172 | N/A | N/A | 57.2 ± 8.2 | 2.46 ± 0.46 | N/A | N/A | 15.1a | 100 |
Lepeule et al. [25] | 756 | 81 + 42b | N/A | 73.3 ± 6.7 | 2.50 ± 0.6 | N/A | 20.5 ± 25.7 | 4 | 0 |
Lange et al. [26] | 663 | 107 | N/A | 72.7 ± 6.7 | 2.70 ± 0.64 | 75 ± 8 | 30.6 ± 24.8 | 7 | 0 |
Marioni et al. [21] | 1091 | N/A | N/A | 69.8 ± 0.78 | 2.36 ± 0.69 | N/A | N/A | N/A | 50.4 |
Wielscher et al. [24] | 204 | 42 | 27 healthy + 34 GOLD grade 0 |
53.4± 13.4c | N/A | N/A | N/A | N/A | 23.2d |
aValue from entire Twins UK cohort obtained from reference [28]
bn COPD patients: 81 chronic bronchitis & 42 emphysema
cInformation provided by the author Wielscher (not available in the original text)
dInformation provided by the author Wielscher (not available in the original text)