Fig. 4.

Expression of adhesion molecule genes in culture of hyaluronan (HA)-coated and uncoated human biliary tree stem cells (hBTSCs). a Gene expression of integrin subunit beta 1 (ITGβ1) in HA-coated hBTSCs (dark gray columns) was higher (days 3 and 7) than uncoated hBTSCs (light gray columns). Data expressed as mean ± SD of n = 5 experiments; §p < 0.01. b Gene expression of integrin subunit beta 4 (ITGβ4) in HA-coated hBTSCs was higher (days 1, 3, 7, and 14) than in uncoated hBTSCs. Data expressed as mean ± SD of n = 5 experiments; *p < 0.05. c Gene expression of E-cadherin (CDH1) in uncoated hBTSCs was higher (day 1) than in HA-coated hBTSCs. Data expressed as mean ± SD of n = 5 experiments; §p < 0.01. d Gene expression of CD44 in uncoated hBTSCs was higher (days 1, 3, and 7) than in HA-coated hBTSCs. Data expressed as mean ± SD of n = 5 experiments; *p < 0.05, §p < 0.01