Table 3.

Vaccine-related inputs.

	Age range (years)
	0–2	3–4	5–17	18–49	50–64	65–74	≥75	Sources
Vaccine acquisition cost per dose ($)a								37
IIV3, public cost	7.75	7.75	7.75	7.52	7.52	7.52	7.52
IIV3, private sector cost	10.69	11.30	11.30	11.90	11.90	11.90	11.90
IIV4, public cost	15.29	13.65	13.65	12.22	12.22	12.22	12.22
IIV4, private sector cost	18.62	16.15	16.15	16.15	16.15	16.15	16.15
Vaccine administration cost ($)								38
Visit costb	46.57	46.57	46.57	46.57	46.57	46.57	46.57
Administration costc	25.08	25.08	25.08	25.08	25.08	25.08	25.08
Cost per vaccine-related AE ($)d								39,41,43
Anaphylaxis	3,864	3,864	3,864	592	636	629	629
Guillain-Barre syndrome	33,427	33,427	33,427	86,237	86,237	86,237	86,237
Vaccine efficacies (IIV3 and IIV4) (%)								8,9,16,44-46
Type A	59.0	59.0	59.0	61.0	61.0	58.0	58.0
Type B included in vaccine	66.0	66.0	77.0	77.0	73.0	69.0	66.0
Type B not included in vaccine	44.0	44.0	52.0	52.0	49.0	47.0	44.0

AE, adverse event; IIV3, trivalent inactivated influenza vaccine; IIV4, quadrivalent inactivated influenza vaccine.

^aThe median public and median private cost for IIV3 and IIV4 indicated for each age group are shown. The model used the weighted average of public and private costs (2014 US dollars), assuming public costs were incurred for 63.2% of those aged <1 year, 55.8% for 1–2 years, 50.9% for 3–6 years, 41.7% for 7–17 years, and 0% for adults (personal communication [unpublished data]: 2010 VFC Eligible Children. Centers for Medicare & Medicaid Services. VFC Comparison of Regional Maximum Rate for Vaccine Administration to Current State Rate. “2010PES_final_8/18/09”).

^bVisit cost based on the average of CPT codes 99213 (physician, $73.08) and 99211 (nurse, $20.06).³⁸

^cVaccine administration cost based on CPT codes 90460 (children) and 90471 (adults).³⁸

^dInflated to 2013 US dollars.⁴³