Table 3.
Molecular characteristics and antibiotic resistance profiles of S. aureus isolated from children with pneumonia.
| CCs | ST (n) | MRSA (n) | MSSA (n) | agr group (n) | spa type (n) | Virulence genes (n) | Antibiotic resistance profile (n) |
|---|---|---|---|---|---|---|---|
| 1 | ST1(2) | IV(1) | 1 | III(2) | t114(1), t127(1) | tst(1), sea(1), seh(1) | P(2), FOT(2), CX(1), E(1), CL(1) |
| 5 | ST764(3) | NT(1) | 2 | II(3) | t002(3) | tst(1), sea(1), seb(1), sec(2), sed(2), seg(2), sei(3), sej(2) | P(3), CN(2), K(2), E(3), FOT(2), CC(2), CX(1), TOB(1), TE(1), MH(1), CIP(1) |
| 6 | ST6(8) | IV(4) | 4 | I(7), II(1) | t15317(1), t304(4), t4793(1), t701(2) | sea(4), eta(1), lukS/F-PV(1) | P(6), CX(4), FOT(5), E(5), CC(1) |
| 7 | ST7(13) | 0 | 13 | I(12), III(1) | t091(10), t605(2), t796(1) | eta(1), sea(1) | P(12), TOB(7), FOT(9), TE(5), E(3), K(2), CN(1), CC(1) |
| 8 | ST8(1), ST630(1), ST1821(1) | V(1) | 2 | I(3) | t9101(1), t4549(1), t3930(1) | sed(1), sej(1) | P(3), FOT(1), E(2), CX(1) |
| 12 | ST12(1) | 0 | 1 | II(1) | t15923(1) | none | P(1), FOT(1), E(1) |
| 15 | ST15(3) | 0 | 3 | II(2), III(1) | t085(1), t491(1), t774(1) | none | P(2), FOT(2), E(1) |
| 20 | ST1281(3) | 0 | 3 | I(3) | t164(2), t731(1) | sec(1), seg(2), sei(3) | P(2)FOT(2) |
| 22 | ST217(1) | 0 | 1 | I(1) | t309(1) | lukS/F-PV(1), seg(1), sei(1) | P(1), FOT(1) |
| 25 | ST25(2) | 0 | 2 | I(2) | t078(2) | sec(1), seg(2), sei(2) | P(2), E(2), TE(1) |
| 30 | ST30(1) | 0 | 1 | I(1) | t338(1) | tst(1), sea(1), seg(1), sei(1) | P(1), FOT(1), E(1) |
| 59 | ST59(35) | IV(31), V(2) | 2 | I(34), II(1) | t163(1), t172(18), t3523(1), t3736(1) t437(10), t441(3), t7281(1) | sea(20), seb(33), lukS/F-PV(3), | P(35), CX(33), FOT(18), E(28), CC(27), K(12), CL(2), TE(7), TOB(1) |
| 72 | ST72(1) | 0 | 1 | I(1) | t148(1) | tst(1), seg(1), sei(1) | None |
| 88 | ST88(5) | IV(2), NT(2) | 1 | III(5) | t1376(1), t15319(1), t2310(3) | none | P(5), FOT(4), CIP(1), CX(4), E(3), K(1), TOB(1) |
| 120 | ST120(1) | V(1) | 0 | IV(1) | t14775(1) | eta(1), seg(1), sei(1) | P(1), CX(1), FOT(1), E(1), CC(1) |
| 188 | ST188(14) | 0 | 14 | I(14) | t15294(1), t189(13) | seb(1), seb(7) | P(13), FOT(5), E(1) |
| 398 | ST398(10) | V(4) | 6 | I(10) | t034(7), t1456(1), t571(2) | lukS/F-PV(1) | P(9), FOT(10), CX(4), E(3) |
| 2315 | ST2315(1) | 0 | 1 | II(1) | t11687(1) | seg(1), sei(1) | P(1), FOT(1), CIP(1) |
CCs, clonal complexes; ST, sequence type by multi-locus sequence typing; SCCmec, Staphylococcal cassette chromosome mec; agr, accessory gene regulator; spa, Staphylococcusprotein A gene; NT, not-typeable; none, no virulence gene detected.
P, penicillin(10 units); CX, cefoxitin (30 μg); CN, gentamicin(10 μg); K, Kanamycin(30 μg); TOB, tobramycin (10 μg); FOT, Fosfomycin-trometamol(200 μg); E, erythromycin (15 μg); TE, tetracycline(30 μg); MH, minocycline(30 μg); CIP, ciprofloxacin(5 μg); CC, clindamycin (2 μg); CL, chloramphenicol(30 μg); None, sensitive to all tested drugs.