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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Leuk Lymphoma. 2016 Jan 19;57(9):2100–2108. doi: 10.3109/10428194.2015.1135435

Table III.

Non-hematologic toxicities regardless of attribution* (Dose Levels 1 and 2)

CDUS Toxicity Type Code All Grades (No. of events) Grade 3 or higher (No. of events)
Infection
 Febrile neutropenia 6 6
 Catheter related infection 2 2
 Pneumonia 4 3
 Sinusitis 1 1
 Skin infection 2 2
 Sepsis 1 1
 Urinary tract infection 1 1
Gastrointestinal
 Diarrhea 14 4
 Vomiting 7 1
 Oral hemorrhage 3 1
Cardiovascular
 Hypotension 3 1
Pulmonary
 Dyspnea 5 1
 Hypoxia 4 3
 Respiratory failure 1 1
 Laryngitis 1 1
 Nasal congestion 4 2
 Stridor 2 2
Neurologic
 Anxiety 2 2
 Delirium 2 2
 Generalized muscle weakness 3 1
Metabolic
 Acidosis 1 1
 Hyperkalemia 1 1
Other
 Fatigue 12 2
 Multi-organ failure 1 1
*

Clinically insignificant and correctable electrolyte abnormalities are not included in this list.