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. 2017 Mar 21;12(3):e0173276. doi: 10.1371/journal.pone.0173276

Table 1. The basic characteristics of the included studies.

Author/Year Groups Sample size Age (median or mean or range) Course of disease Course of treatment (days) Intervention Type of psoriasis Outcomes
Zhou and Huang, 2005[30] EG 143 18–60 4–28 years 28 Coptis chinensis, 10 g; Phellodendron, 20 g; Sophora flavescens, 20 g; garden burnet, 20 g; mahoni, 60 g; pomegranate rind, 15 g; broom cypress fruits, 15 g; groundsel 30 g. (1)
CG 129 18–61 5–30 years 28 UV-A (1)
Liu et al., 2005[31] EG 88 13–60 6.06 years 40 Medicated bath: 30 minutes+NB-UVB (1)
CG 78 14–58 6.22 years 40 NB-UVB (1)
Liu et al., 2005[32] EG 40 15–69 6.8 years 40 Cynanchum paniculatum, 30 g; Fructus Kochiae, 30 g; purslane, 30 g; Cortex Dictamni, 30 g; white hellebore, 30 g. (1)
CG 40 10–65 2.0 years 40 Medicated bath: 30 minutes+NB-UVB (1)
Liu et al., 2005[32] EG 72 12–62 7.36 years 40 NB-UVB (1)
CG 65 13–69 7.05 years 40 Cynanchum paniculatum, 30 g; Fructus cnidii, 30 g; Sophora flavescens, 30 g; Zanthoxylum, 30 g; Patrinia, 30 g; Polygonum cuspidate, 30 g; purslane, 30 g; salvia, 20 g; Atractylodes, 15 g. (1)
Liu et al., 2008[34] EG 89 13–60 6.72 years 28 Medicated bath: 30 minutes+NB-UVB (1) ①②③
CG 96 14–58 7.23 years 28 NB-UVB (1)
Cui et al., 2008[35] EG 62 45.82±13.89 5.77±4.95 months 56 Medical stone. Medicated bath: 20 minutes+NB-UVB (1) ①③④
CG 57 38.72±12.17 4.47±3.76 months 56 NB-UVB (1)
Sun et al., 2010[36] EG 35 18–60 6.72 years 56 Salvia, 30 g; Angelica sinensis, 30 g; selfheal, l30 g; Fructus Kochiae, 30 g; Cortex Dictamni, 30 g; golden cypress, 30 g; Folium Isatidis, 30 g; Smilax glabra, 30 g. (1) ①③④
CG 33 19–58 7.23 years 56 Medicated bath: 30 minutes+NB-UVB (1)
Zhang et al., 2010[37] EG 30 15–60 10.37±9.59 days 56 NB-UVB (1) ①④
CG 30 12–58 10.85±10.46 days 56 Galla chinensis, golden cypress, Angelica sinensis, turmeric, Fructus Psoraleae. (1)
Luo et al., 2010[38] EG 88 -- -- 60 Medicated bath: 20 minutes+NB-UVB (1) ①②③
CG 85 -- -- 60 NB-UVB (1)
Lin et al., 2010[39] EG 95 29.52±6.38 8.25±3.16 year 48 Golden cypress, 30 g; purslane, 30 g; salvia, 30 g; Cortex Dictamni, 30 g; Angelica sinensis, 30 g. Medicated bath: 30 minutes+NB-UVB (1) ①③④
CG 90 27.42±6.28 7.48±2.86 years 48 NB-UVB (1)
Shi et al., 2011[40] EG 170 7–70 12.9 years 56 Sophora flavescens, 100 g; Fructus cnidii, 50 g; Rehmannia, 50 g; Chrysanthemum indicum, 100 g; Rhizoma Curcumae, 50 g; mirabilite, 200 g; Herba Speranskiae Tuberculatae, 100 g; Chinese mugwort leaf, 100 g. Medicated bath: 20 minutes+NB-UVB (1) ①②③
CG 168 8–65 13.5 years 56 NB-UVB (1)
Song et al., 2011[41] EG 193 48.2±11.5 6.52 years 28 Salvia, safflower, Rehmannia, Folium Isatidis, Cortex Moutan, Smilax glabra, red peony root, Angelica sinensis, Sparganium stoloniferum, Rhizoma Curcumae, Caulis Spatholobi, Capsicum annuum, dried alum. (1) ①②④
CG 190 50.2±8.6 7.23 years 28 Medicated bath: 30 minutes+NB-UVB (1)
Qu et al., 2011[42] EG 95 36±12.4 5.7±3.2 years 40 NB-UVB (1) ①③④
CG 95 35±12.7 6.2±3.5 years 40 Smilax glabra, 30 g; Fructus Kochiae, 15 g; Angelica sinensis, 20 g; Cortex Dictamni, 20 g; Cynanchum paniculatum, 20 g; Sophora flavescens, 15 g; Fructus cnidii, 20 g; cocklebur fruit, 15 g; Radix stemonae, 15 g; Cortex Pseudolaricis, 10 g; Tribulus terrestris, 15 g; rhubarb, 10 g. (1)
Wang et al., 2011[43] EG 50 18–65 8.6 years 28 Medicated bath: 20–30 minutes+NB-UVB (1) ①③
CG 50 19–60 7.8 years 28 NB-UVB (1)
Wang et al., 2012[44] EG 30 16–68 1 month-25 years 30 Speranskiae Tuberculatae, Cacumen Biotae, Cortex Dictamni, salvia, Angelica sinensis, peach seed, Sophora flavescens, Fructus Kochiae, pearl powder. Medicated bath: 20 minutes+NB-UVB (1) ①③④
CG 30 21–70 2 months-20 years 30 NB-UVB (1)
Re et al., 2012[45] EG 42 19–58 -- 40 Gentiana macrophylla, 30 g; Acorus tatarinowii, 30 g; Sophora flavescens, 30 g; Dioscorea nipponica Makino, 30 g; paniculate swallowwort root, 30 g; Cacumen Biotae, 30 g; paper mulberry fruit leaves, 30 g; figwort root, 30 g. Medicated bath: 30 minutes+ (1)
CG 40 19–58 -- 40 NB-UVB (1)
Han et al., 2013[46] EG 75 17–59 35 days-34 years 40 NB-UVB (1) ①③④
CG 75 18–58 28 days-35 years 40 pine tar (10%). Medicated bath: 20 minutes+NB-UVB (1)
Wang, 2013[47] EG 112 39.75±10.69 5.46±1.24 years 20 NB-UVB (1) ①③④
CG 56 38.98±11.23 5.69±1.29 years 20 Radix scutellariae, Patrinia, dandelion, red peony root, Paeonia suffruticosa, salvia, Radix asparagi, Radix rehmaniae recens, Cortex Dictamni, Fuctus Kochiae, Atractylodes. (1)
Wang et al., 2013[48] EG 60 -- -- 56 Medicated bath: 30 minutes+ (1)
CG 63 -- -- 56 NB-UVB (1)
Li, 2014[49] EG 32 46.45±13.43 5.46±4.67 months 56 NB-UVB (1) ①④
CG 32 46.45±13.43 5.46±4.67 months 56 the bark of ash, 100 g. Medicated bath: 20–30 minutes+ (1)
Wang and Gao, 2014[50] EG 53 -- -- 45 NB-UVB (1) ①④
CG 50 -- -- 45 NB-UVB (1)
Luo et al., 2014[51] EG 56 -- -- 24 Angelica sinensis, 30 g; salvia, 30 g; Fructus Kochiae, 30 g; selfheal, 30 g; golden cypress, 30 g; Cortex Dictamni, 30 g; Smilax glabra, 30 g; Folium isatidis, 30 g. (1) ①②③
CG 52 -- 24 Medicated bath: 30 minutes+NB-UVB (1)
Zhou and Yin, 2014[52] EG 42 46.2±2.3 56 NB-UVB (1) ①③
CG 42 46.2±2.3 56 Sophora flavescens, Chrysanthemum indicum, Cynanchum paniculatum, Viola philippica, Fructus cnidii, honeysuckle, Radix glycyrrhizae. (1)
Zhang, 2014[53] EG 57 35.2±6.7 -- Medicated bath: 15–20 minutes+ (1) ①④
CG 55 37.1±6.2 -- NB-UVB (1)
Zhao et al., 2015[54] EG 30 21.64±8.9 -- NB-UVB (1)
CG 30 23.64±6.9 -- pine tar (10%). Medicated bath: 20 minutes+NB-UVB (1)

(1) psoriasis vulgaris;

① total effective rate; ② recurrence rate; ③ incidence of adverse reactions; and ④ psoriasis area and severity index.

EG: experimental group, CG: control group.