Table 4. Correlation analysis of the abundance of UFAs and CERAD and Braak scores.
Region | Fatty acid | Braak (tau) | CERAD (Aβ) | ||
---|---|---|---|---|---|
r | p-value | r | p-value | ||
Cerebellum | EPA | −0.31 | 0.096 | −0.35 | 0.055 |
Linoleic | −0.13 | 0.497 | −0.19 | 0.306 | |
Arachidonic acid | −0.11 | 0.559 | −0.19 | 0.033 | |
Oleic acid | −0.28 | 0.133 | −0.27 | 0.142 | |
DHA | 0.41 | 0.024 | 0.34 | 0.068 | |
Linolenic acid | −0.36 | 0.053 | 0.30 | 0.108 | |
ITG | EPA | −0.33 | 0.042 | −0.36 | 0.028 |
Linoleic | −0.38 | 0.018 | −0.35 | 0.032 | |
Arachidonic acid | −0.38 | 0.020 | −0.37 | 0.025 | |
Oleic acid | −0.34 | 0.040 | −0.35 | 0.034 | |
DHA | 0.31 | 0.058 | 0.32 | 0.048 | |
Linolenic acid | −0.26 | 0.115 | −0.32 | 0.052 | |
MFG | EPA | −0.61 | <0.001 | −0.53 | <0.001 |
Linoleic | −0.57 | <0.001 | −0.58 | <0.001 | |
Arachidonic acid | −0.56 | <0.001 | −0.55 | <0.001 | |
Oleic acid | −0.64 | <0.001 | −0.64 | <0.001 | |
DHA | 0.60 | <0.001 | −0.69 | <0.001 | |
Linolenic acid | −0.63 | <0.001 | −0.67 | <0.001 |
Relationships between global measures of amyloid and tau pathologies and the regional abundances of six UFAs, values highlighted in bold are significant at p < 0.05.