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. 2017 Mar 21;14(3):e1002266. doi: 10.1371/journal.pmed.1002266

Table 4. Correlation analysis of the abundance of UFAs and CERAD and Braak scores.

Region Fatty acid Braak (tau) CERAD (Aβ)
r p-value r p-value
Cerebellum EPA −0.31 0.096 −0.35 0.055
Linoleic −0.13 0.497 −0.19 0.306
Arachidonic acid −0.11 0.559 0.19 0.033
Oleic acid −0.28 0.133 −0.27 0.142
DHA 0.41 0.024 0.34 0.068
Linolenic acid −0.36 0.053 0.30 0.108
ITG EPA 0.33 0.042 0.36 0.028
Linoleic 0.38 0.018 0.35 0.032
Arachidonic acid 0.38 0.020 0.37 0.025
Oleic acid 0.34 0.040 0.35 0.034
DHA 0.31 0.058 0.32 0.048
Linolenic acid −0.26 0.115 −0.32 0.052
MFG EPA 0.61 <0.001 0.53 <0.001
Linoleic 0.57 <0.001 0.58 <0.001
Arachidonic acid 0.56 <0.001 0.55 <0.001
Oleic acid 0.64 <0.001 0.64 <0.001
DHA 0.60 <0.001 0.69 <0.001
Linolenic acid 0.63 <0.001 0.67 <0.001

Relationships between global measures of amyloid and tau pathologies and the regional abundances of six UFAs, values highlighted in bold are significant at p < 0.05.