Fig 5. Resveratrol does not alter CYP17 and CYP21 expression via PKB signaling.
H295R cells were treated with 5μM or 10μM resveratrol (RSV) for 6h. Total and phosphorylated PKB protein expression was assessed by Western blot analysis. A. H295R cells grown under starvation (SM) showed a dose-dependent downregulation of PKB phosphorylation after RSV treatment. B. In H295R cells grown under normal growth (GM) condition no effect of RSV on PKB phosphorylation was observed.