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No effect of chronic hyperglycemia on primary T-cell responses to alloantigen. A: PLN cell counts in alloimmunized mice. B: CD4+ and CD8+ cell counts in PLN. C: Frequency of responding Ki67+CD44hi cells in PLN. D: Geometric mean fluorescence intensity (gMFI) of IFNγ in Ki67+CD44hi cells. Black bars, B6; white bars, Akita. n = 6–8 per group from seven independent experiments. No significant differences after multiple Student t tests with Bonferroni-Dunn corrections.
