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. 2017 Feb 13;39(3):629–635. doi: 10.3892/ijmm.2017.2887

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Copyright: © Bian et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Angiotensin II (Ang II) stimulates the expression of molecules involved in low-density lipoprotein (LDL) transcytosis. Human umbilical vein endothelial cells (HUVECs) were pretreated with methyl-β-cyclodextrin (MβCD) or dithiothreitol (DTT) for 30 min, and then stimulated with or without Ang II for 24 h. (A) Representative western blots showing the expression of LDL receptor (LDLR), caveolin-1, cavin-1 and clathrin. (B) Quantitative analysis of the expression of proteins. ^*P<0.05 vs. control; ^#P<0.05 vs. Ang II.