Figure 1.

Structure of fisetin and effects on cell migration and apoptosis in primary cultured astrocytes. (A) Chemical structure of fisetin. (B) Quantification of the astrocyte apoptotic rate following treatment with various concentrations of fisetin. (C) Apoptosis of astrocytes treated with or without fisetin for 24 h as detected by flow cytometry. Fisetin at concentrations ranging from 12.5–50 µM (panels b–d) did not significantly affect cell apoptosis following treatment for 24 h compared to the control group (panel a).