Table 2.
Difference detection of putative metabolites using SID-MRM-MS
Metabolite | Fold change | Comparison groups | Mode | P value |
---|---|---|---|---|
PC ae C38:4 | ↓ | NC versus Converterpre | POS | 0.00417 |
Proline | ↓ | NC versus Converterpre | POS | 0.00003 |
Lysine | ↓ | NC versus Converterpre | POS | 0.0020 |
Serotonin | ↓ | NC versus Converterpre | POS | 0.0160 |
Taurine | ↓ | NC versus Converterpre | POS | 0.0030 |
DOPA | ↑ | NC versus Converterpre | POS | 0.0001 |
Phenylalanine | ↓ | NC versus Converterpre | POS | 0.00001 |
Acylcarnitine C7-DC | ↓ | NC versus aMCI/AD | POS | 0.0001 |
The arrows indicate upregulation or downregulation in the comparison group as compared to the NC participants. DOPA, dihydroxyphenylalanine; C7-DC, pimelyl-l-carnitine.