Table 2.

Effect of the exercise program vs. usual care on study endpoints, adjusted for study site and baseline value, mean (95% CI).

Outcomes	Month	Exercise	Control	p-value
Physical Activity (min/wk)
Overall (N=188)
	Baseline	140.2 (107.0, 173.3)	108.5 (77.7, 139.3)	0.18
	Change at 3 months	+127.0 (93.0, 160.0)	−5.8 (−39.0, 27.3)	< .0001
Subgroup: Baseline Physical Activity < 150 min/wk, N = 124
	Baseline	33.5 (20.7, 46.2)	35.0 (23.0, 47.1)	0.86
	Change at 3 months	+165.2 (121.6, 208.8)	+23.9 (−13.9, 61.7)	<0.0001
Subgroup: Baseline Physical Activity ≥ 150 min/wk, N = 62
	Baseline	293.4 (246.1, 340.7)	325.8 (271.3, 380.3)	0.38
	Change at 3 months	+43.2 (−6.2, 92.7)	−54.4 (−116.8, 8.0)	0.01
Six Minute Walk Test (6MWT) (meters)
	Baseline	485 (469, 501)	481 (459, 503)	0.75
	Change at 3 months	+33.8 (19.6, 47.9)	+4.9 (−9.1, 18.8)	0.004
YMCA Sessions		20.1 (3.3)
FACT-General
	Baseline	90.4 (87.5, 93.4)	88.3 (85.7, 91.0)	0.29
	Change at 3 months	+1.6 (−0.2, 3.3)	−1.0 (−2.8, 0.8)	0.039
FACT-Fatigue
	Baseline	42.0 (40.0, 43.9)	40.4 (38.1, 42.5)	0.38
	Change at 3 months	+1.6 (0.1, 3.0)	+0.8 (−0.7, 2.2)	0.42
BMI (kg/m2)
	Baseline	28.9 (27.7, 30.0)	29.2 (28.0, 30.5)	0.66
	Change at 3 months	−0.1 (−0.3, 0.1)	−0.1 (−0.3, 0.1)	0.84
% Body Fat
	Baseline	39.1 (37.4, 40.9)	40.2 (38.4, 42.0)	0.39
	Change at 3 months	−0.3 (−0.8, 0.2)	−0.2 (−0.7, 0.4)	0.66
Lean Mass (kg)
	Baseline	44.25 (42.06, 46.45)	43.87 (41.72, 46.03)	0.81
	Change at 3 months	−0.282 (0, 0.454)	+0.015 (−0.745, 0.775)	0.58
Bone Mineral Density (g/cm2)
	Baseline	1.171 (1.141, 1.201)	1.163 (1.128, 1.199)	0.73
	Change at 3 months	+0.009 (0.003, 0.016)	+0.001 (−0.005, 0.008)	0.09
Insulin (uU/mL)
	Baseline	15.87 (12.71, 19.03)	15.19 (13.37, 17.00)	0.71
	Change at 3 months	−0.38 (−1.90, 1.14)	−0.90 (−2.41, 0.62)	0.62
CRP (mg/L)
	Baseline	4.53 (3.18, 5.87)	5.49 (3.56, 7.42)	0.42
	Change at 3 months	−1.36 (−2.41, −0.31)	−1.27 (−2.32, −0.23)	0.88