Table 4.
Relative hazards* of breast cancer outcomes by type of social tie in women in the ABCPP
| N | Recur | HR | 95% CI |
Breast cancer- specific mortality |
HR | 95% CI | Total mortality |
HR | 95% CI |
||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Older White** | |||||||||||
| Married/partner | 2,810 | 432 | 1.00 | 284 | 1.00 | 540 | 1.00 | ||||
| No partner | 688 | 109 | 0.97 | (0.77, 1.23) | 99 | 1.37 | (1.06, 1.77) | 201 | 1.45 | (1.21, 1.74) | |
| p-value† | 0.81 | 0.02 | <0.001 | ||||||||
| Non-White and Younger White** | |||||||||||
| Married/partner | 4,479 | 697 | 1.00 | 474 | 1.00 | 595 | 1.00 | ||||
| No partner | 1,260 | 210 | 0.90 | (0.77, 1.06) | 133 | 0.92 | (0.75, 1.13) | 185 | 0.93 | (0.78, 1.11) | |
| p-value | 0.22 | 0.42 | 0.42 | ||||||||
| p-interaction | 0.66 | 0.02 | 0.001 | ||||||||
| White | |||||||||||
| Large friend network | 3,248 | 529 | 1.00 | 333 | 1.00 | 545 | 1.00 | ||||
| Moderate friend network | 1,773 | 292 | 1.01 | (0.87, 1.17) | 193 | 1.02 | (0.85, 1.22) | 303 | 0.96 | (0.83, 1.11) | |
| Small friend network | 1,171 | 203 | 1.06 | (0.89, 1.24) | 139 | 1.04 | (0.85, 1.28) | 237 | 1.04 | (0.89, 1.22) | |
| p-value | 0.56 | 0.66 | 0.64 | ||||||||
| Non-White | |||||||||||
| Large friend network | 1,865 | 222 | 1.00 | 174 | 1.00 | 217 | 1.00 | ||||
| Moderate friend network | 620 | 97 | 1.15 | (0.89, 1.47) | 72 | 1.09 | (0.81, 1.45) | 111 | 1.35 | (1.06, 1.71) | |
| Small friend network | 560 | 105 | 1.43 | (1.12, 1.84) | 79 | 1.40 | (1.05, 1.86) | 108 | 1.43 | (1.12, 1.83) | |
| p-value | 0.002 | 0.01 | <0.001 | ||||||||
| p-interaction | 0.02 | 0.08 | 0.01 | ||||||||
| Older White and Asian | |||||||||||
| No community ties | 3,816 | 546 | 1.00 | 447 | 1.00 | 735 | 1.00 | ||||
| Community ties | 2,020 | 284 | 0.93 | (0.77, 1.11) | 179 | 0.80 | (0.65, 0.99) | 321 | 0.79 | (0.68, 0.92) | |
| p-value | 0.39 | 0.04 | 0.003 | ||||||||
| Younger White, Black, Hispanic | |||||||||||
| No community ties | 2,010 | 345 | 1.00 | 193 | 1.00 | 263 | 1.00 | ||||
| Community ties | 1,391 | 273 | 1.13 | (0.95, 1.34) | 171 | 1.18 | (0.94, 1.48) | 202 | 1.12 | (0.91, 1.37) | |
| p-value | 0.17 | 0.16 | 0.28 | ||||||||
| p-interaction | 0.15 | 0.003 | <0.001 | ||||||||
| All groups‡ | |||||||||||
| Religious participation | 4,669 | 763 | 1.00 | 473 | 1.00 | 775 | 1.00 | ||||
| No religious participation | 2,452 | 423 | 1.03 | (0.91, 1.18) | 269 | 1.07 | (0.91, 1.26) | 436 | 1.06 | (0.94, 1.21) | |
| p-value | 0.62 | 0.39 | 0.35 | ||||||||
| White | |||||||||||
| Large relative network | 3,016 | 497 | 1.00 | 322 | 1.00 | 501 | 1.00 | ||||
| Moderate relative network | 1,509 | 237 | 1.00 | (0.84, 1.18) | 161 | 1.00 | (0.82, 1.22) | 274 | 1.02 | (0.87, 1.20) | |
| Small relative network | 1,667 | 290 | 0.99 | (0.85, 1.15) | 182 | 0.86 | (0.71, 1.04) | 310 | 0.97 | (0.83, 1.12) | |
| p-value | 0.86 | 0.14 | 0.77 | ||||||||
| Non-White | |||||||||||
| Large relative network | 1,713 | 224 | 1.00 | 170 | 1.00 | 230 | 1.00 | ||||
| Moderate relative network | 514 | 86 | 1.33 | (1.02, 1.73) | 68 | 1.42 | (1.05, 1.92) | 91 | 1.38 | (1.06, 1.78) | |
| Small relative network | 818 | 114 | 1.21 | (0.95, 1.54) | 87 | 1.33 | (1.01, 1.76) | 115 | 1.35 | (1.06, 1.72) | |
| p-value | 0.07 | 0.02 | 0.003 | ||||||||
| p-interaction | 0.21 | 0.03 | 0.05 | ||||||||
Analyses of recurrence do not include 30 women with stage IV cancer.
*
Models adjusted for covariates in Table 2, Model III and simultaneously adjusted for the different social ties. Analyses adjusted for variables other than those specifically analyzed or restricted.
**
Older whites included white women older than the median age=56.1. Younger whites included white women younger than the median age.
†
p-value=p-value, dichotomous or ordinal variable; p-interaction=p-value, test for interaction
‡
This value does not include data from the SBCSS study which did not include data on religious participation.