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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: J Immunol. 2017 Feb 24;198(7):2854–2864. doi: 10.4049/jimmunol.1602006

Figure 6. ROS regulate TG-induced reactive granulopoiesis via a paracrine mechanism.

Figure 6

(A) ROS may regulate reactive granulopoiesis both autonomously and non-autonomously. (B) The schematic of the BM transplantation experiment. The percentages of donor derived (CD45.1+) cells among PB mononuclear cells in WT and CGD mice are shown. Data represent the means ± SD of n = 5 mice per group. (C) Flow cytometry-based lineage analysis of the CD45.1 (donor) and CD45.2 (recipient) BM cells. Data shown are mean ± SD of n=5 mice. * p<0.01 versus control (PBS treated mice). (D) Measurement of cycling cells in each progenitor population by incorporation of BrdU. Data shown are means ± SD of n=5 mice. * p<0.01versus control (PBS treated mice).